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SCIENTIFIC
EVALUATION
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BLUEGUARD ORAL

BLUEGUARD- ORAL REVERSE BLUE LIGHT CYTOTOXIC EFFECTS

BlueGuard-Oral inhibits Lactate Dehydrogenase (LDH) leak to the cytosol, an indicator for cell damage due to stress (blue light)

BlueGuard-Oral effect on cellular recovery from blue light induced cytotoxicity
PRODUCT
BLUEGUARD- ORAL
IN VITRO STUDY

ABOUT
Protection against blue light stress induced inflammation via expression of the inflammatory marker TNF-a
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Cell culture: Normal Human Keratinocytes
Product application: 200 μg/ml BlueGuard-Oral for 48h
Stress: Blue LED 415 nm (3 mW/cm2 - 18min) at 24h and 48h
Evaluation: fluorescence intensity staining
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TNF-a expression
untreated
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TNF-a expression
under blue light stress

TNF-a expression
blue light stress +
BlueGuard-Oral 200 μg/ ml
Expression of the angiogenic protein – VEGF as indication for cell regeneration and vitality
Cell culture: Normal Human Keratinocytes
Product application: 200 μg/ml BlueGuard-Oral for 48h
Stress: Blue LED 415 nm (3 mW/cm2 - 18min) at 24h and 48h
Evaluation: fluorescence intensity staining
,
​


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VEGF expression
untreated
VEGF expression
under blue light stress

VEGF expression
blue light stress +
BlueGuard-Oral 200 μg/ ml
FEATURED
CONTACT
BlueGuard-Oral Anti Blue
Light Protection
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BlueGuard-Oral
Safety Profile

DEMO
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